Ivanov Petr Alexeevich,Gasanova Tatiana Vladimirovna,Petukhova Natalia Vitalievna
申请号:
US201715607189
公开号:
US10117923(B2)
申请日:
2017.05.26
申请国别(地区):
美国
年份:
2018
代理人:
Keddie James S.`Bozicevic, Field & Francis LLP
摘要:
Provided herein is a recombinant rod-shaped viral particle comprising a fusion protein comprising a coat protein for a rod-shaped plant virus and a epitope from a human and/or human pathogen, where the epitope is disposed on the outer surface of the viral particle. In certain cases, the amino acid sequence of the coat protein is at least 40% identical to the amino acid sequence of the Tobacco Mosaic Virus (TMV) coat protein.