PATIENCE, DANIEL B.,PETERSON, MATTHEW,ZHENG, FENGMEI,LYSSIKATOS, JOSEPH P.,MARX, ISAAC,PRINCE, ROBIN,MA, BIN,HOPKINS, BRIAN T.
申请号：
ARP180100935
公开号：
AR111594A1
申请日:
2018.04.13
申请国别(地区):
AR
年份:
2019
代理人:
摘要：
Claim 1: A formula compound (1),Or an acceptable salt for a drug, in which ring A is a single-ring heteromorph consisting of five members, consisting of three independently selected heteromorphs from N to S, in which the single-ring heteromorphism of five members is replaced by one or more R1；Q1,Q2 and Q3 are independently selected from O, N (r2) and CH-R3.There are at least two Q1,Q2 and Q3 are C-R3；W was selected from CH and N； from CH and N； R1 was selected from C83218D83318326 and carbohydrates independently of 3 to 5 members in each case, and the carbohydrates of C83216C83318326 and 3 to 5 members could be replaced by R830404 with 1 or more；R830404, in each case, is independent of the halo selection - CN, C832183312626 and 3 to 5 members of the carbon thyroid； Ris selected from H, C8321833131 and C832626.Alquenilo C83228331-832626；1.C 83228331 asphalt；1.4 to 6 members of the monocyclic thyroid gland and 4 to 6 members of the monocyclic isopropylene,- C(O) 8322； - 74919；- C (O) N (R 74919) 8322；- S(O) 83228R749；Y-S (O) 8322； N (RS74919) 8322；There, the lessor C8321831832626,Alquenilo C83228331-832626；1.C 83228331 asphalt；4-6 members of monocyclic thyroid gland and 4-6 members of monocyclic isopropylene can be replaced by one or more r830404.2. Each publication is independent of H, C 832183318326；Alquenilo C83228331-832626；1.C 83228331 asphalt；Monocyclic carbohydrates of 4-6 members and heterocyclic carbohydrates of 4-6 members, of which C83218C8331832626；Alquenilo C83228331-832626；1.C 83228331 asphalt；Single-ring thyroid gland of 4-6 members and single-ring isocyclic propylene of 4-6 members can be replaced independently at a rate of 830404 or more.Each emergence is selected independently of asphalt C83218331832626.Alquenilo C83228331-832626；1.C 83228331 asphalt；1.4 to 6 members of the monocyclic thyroid gland, 4 to 6 members of the monocyclic isopropylene, HALO, -CN, -C(O) R 830491；- C(O) 8322； - 8304； - 74919；- C (O) N (R 83040)； 7491832222；- N (R. 83040)； 749
