The present invention relates to a novel lactic acid bacteria strain Lactobacillus plantarum KBL396) KCTC13278BP, a composition comprising at least one selected from the group consisting of a culture of the strain, a lysate of the strain, and an extract of the strain, and a use thereof in foods and drugs. A strain and a composition according to the present invention exhibits excellent effects on the alleviation of neurological disorders, specially mental disorders and neurodegenerative disorders, and have no risks of side effects in the human body, thereby finding useful application in the alleviation of neurological disorder.