CHRIS BLACKBURN,COURTNEY A. CULLIS,FRANCOIS SOUCY,GANG LI,HE XU,INDU T. BHARATHAN,JANICE LEE,JEFFREY P. CIAVARRI,JOUHARA CHOUITAR,KENNETH M. GIGSTAD,KRISTA E. GIPSON,MANSOUREH REZAEI,MARIO GIRARD,MICH
申请号:
BR112016016289
公开号:
BR112016016289A2
申请日:
2015.01.13
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention provides a compound of formula I: and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.