A hand control assembly for an intravascular catheter system includes a controller and a plurality of spaced apart hand-actuated members. The intravascular catheter system includes a control console that is configured to be positioned on a support surface. Each hand-actuated member is configured to be manually actuated and is positioned away from the control console and support surface. The hand control assembly controls varying stages of an ablation procedure, including an inflation stage, ablation stage, thawing stage and/or time to isolation. Each hand-actuated member sends at least one (i) initiation signal to the controller to initiate at least one of the inflation stage, ablation stage and/or a calculation of time to isolation, and/or (ii) termination signal to the controller to terminate at least one of the inflation stage, ablation stage and/or thawing stage.