חומרים נגד פטריות 5, 6 – דיהידרו – 4h – פירולו [1, 2 –a] [4,1] בנזו–דיאזפינים ו 6h – פירולו[2,1–a] בנזודיאזפינים מותמרים עם תולדות הטרוציקליות

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专利权人:

JANSSEN PHARMACEUTICA NV

发明人:

申请号：

IL22918113

公开号：

IL229181A

申请日:

2013.10.31

申请国别(地区):

IL

年份:

2015

代理人:

摘要：

The present invention is concerned with novel antifungal 5,6-dihydro-4H-pyrrolo-[1,2-a][1,4]benzodiazepines and 6H-pyrrolo[1,2-a][1,4]benzodiazepines substituted with heterocyclic derivatives of Formula (I) wherein R1, R2, R3, R4 and Het have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/