MEERPOEL LIEVEN,MAES LOUIS JULES ROGER MARIE,DE WIT KELLY,AUGUSTYNS KOEN JAN LUDOVICUS
申请号:
IN2200/MUMNP/2013
公开号:
IN2013MN02200A
申请日:
2013.11.25
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention is concerned with novel antifungal 5 6 dihydro 4 pyrrolo [1 2 ][1 4]benzodiazepines and 6 pyrrolo[1 2 ][1 4]benzodiazepines substituted with heterocyclic derivatives of Formula (I) wherein R R R R and Het have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.