VAN ZANDT, Michael,GOLEBIOWSKI, Adam,JI, Min, Koo,WHITEHOUSE, Darren,RYDER, Todd,BECKETT, Paul,邁克爾.范贊特,亞當.戈文比奧夫斯基,邱池民,達倫.懷特豪斯,托德.賴德,保羅.貝克特
申请号:
HK16101953.5
公开号:
HK1213901A
申请日:
2016.02.22
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
Compounds according to Formula I and Formula II are potent inhibitors of Arginase I and II activity: where R1, R2, R3, R4, R5, R6, R7, R8, R9, D, M, X, and Y are defined as set forth in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use for treating or preventing a disease or a condition associated with arginase activity.