PICKFORD, LESLEY B.,BEBBINGTON, CHRISTOPHER R.,YARRANTON, GEOFFREY T.,KING, DAVID
申请号:
CA2522957
公开号:
CA2522957C
申请日:
2004.04.23
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Compositions and methods for the therapy of Inflammatory Bowel Disease (IBD),including Celiac Disease, Crohn~s Disease, and Ulcerative Colitis, aredisclosed. Illustrative compositions comprise one or more anti-type 1interferon antagonists, such as anti-type 1 interferon receptor antibodyantagonists and fragments thereof, as well as polypeptides and small moleculesthat inhibit the interaction of type 1 interferon with its receptor (IFNAR).