Kim, Sung Wuk,Park, Seung Kook,Jeong, Jae Kap,Ahn, Hyea Kyung,Kim, Min Sun,Kim, Eun Sun,Yong, Hae-Young,Shin, Dongok,Song, Yeon Jung,Yoo, Tae Hyoung
申请号：
NZ73766615
公开号：
NZ737666A
申请日:
2015.04.30
申请国别(地区):
NZ
年份:
2018
代理人:
摘要：
The present disclosure relates to an isolated anti-FcRn antibody, which is an antibody binding to FcRn (stands for neonatal Fe receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmune diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases.
