A system for testing motor and/or performance of a human subject with a mobile device is provided. The system features a mobile device including a processor subsystem and configured to receive taps from a hand or part of a hand of a human subject on a screen of the mobile device. A tap application for the mobile device is executed by the processor subsystem and is responsive to taps by the hand or part of the hand on the screen and is configured to measure the frequency and duration of each tap by the hand or part of the hand on the screen to determine the motor and/or cognitive performance of the human subject.