ANTIBODY-DRUG CONJUGATE

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专利权人:

DAIICHI SANKYO COMPANY; LIMITED

发明人:

MASUDA, Takeshi,NAITO, Hiroyuki,NAKADA, Takashi,YOSHIDA, Masao,ASHIDA, Shinji,MIYAZAKI, Hideki,KASUYA, Yuji,MORITA, Koji,ABE, Yuki,OGITANI, Yusuke

申请号：

PH12015500667

公开号：

PH12015500667B1

申请日:

2015.03.25

申请国别(地区):

PH

年份:

2015

代理人:

摘要：

As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH-(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the anti-tumor compound is connected to the terminal of Lc the nitrogen atom of the amino group at position 1 as a connecting position.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/