Shahrokh Zahra,Calias Pericles,Pan Jing,Powell Jan,Charnas Lawrence,Mccauley Thomas,Wright Teresa Leah,Pfeifer Richard
申请号：
NZ70280311
公开号：
NZ702803A
申请日:
2011.06.25
申请国别(地区):
NZ
年份:
2017
代理人:
摘要：
Disclosed is a composition for intrathecal administration comprising a replacement enzyme for treating a lysosomal storage disease associated with reduced level or activity of a lysosomal enzyme, wherein the replacement enzyme is present in the composition at a concentration at or greater than about 10 mg/ml, the composition comprises phosphate at a concentration no greater than 50 mM.
