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Oral compositions comprising beta-escin for reducing acetaldehyde toxicity
专利权人:
ESCILAB SP. Z O.O.
发明人:
Katarzyna Koziak
申请号:
US16461967
公开号:
US10799550B2
申请日:
2017.11.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to an oral liquid composition comprising β-escin (beta-escin) and chokeberry fruit extract for use in treatment and prevention of conditions related to the increased acetaldehyde toxicity, such as veisalgia, alcohol poisoning, esophageal cancer, oropharyngolaryngeal cancer or a condition resulting from insufficient aldehyde dehydrogenase (ALDH) enzyme activity. Administration of the composition of the invention to a subject results in an increased metabolism of aldehydic substrates, in particular those originating from catabolism of alcohol and representing a hazard to humans due to their toxicity.
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