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1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro- 4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo [4,5-b]pyridin-7-yloxy)-phenyl] -urea and related compounds and their use in therapy
专利权人:
Royal Cancer Hospital (The);Institute of Cancer Research;Institute of Cancer Research: Royal Cancer Hospital (The);Cancer Research Technology Limited
发明人:
Springer, Caroline,Niculescu-Duvaz, Ion,Marais, Richard,Niculescu-Duvaz, Dan,Zambon, Alfonso,Menard, Delphine
申请号:
AU2011209586
公开号:
AU2011209586A1
申请日:
2011.01.27
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain compounds of the following formula (I) (for convenience, collectively referred to herein as "IP compounds"), which, , are useful in the treatment of cancer, e.g., cancer characterised by (e.g., driven by) mutant RAS ("mutant RAS cancer"). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions in the treatment of cancer, e.g., mutant RAS cancer.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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