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1-(5-TERT-BUTYL-2-PHENYL-2H-PYRAZOL-3-[2-FLUORO-4-(1-METHYL-2-OXO-2,3-DIHYDRO-1H-IMIDAZO[4,5-B]PYRIDIN-7-YLOXY)-PHENYL]-UREA AND RELATED COMPOUNDS AND THEIR USE IN THERAPY
专利权人:
CANCER RESEARCH TECHNOLOGY LTD;INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE)
发明人:
SPRINGER CAROLINE,NICULESCU-DUVAS ION,MARAIS RICHARD,NICULESCU-DUVAS DAN,ZAMBON ALFONSO,MENARD DELPHINE
申请号:
ZA201205181
公开号:
ZA201205181B
申请日:
2012.07.12
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain compounds of the following formula (I) (for convenience, collectively referred to herein as “IP compounds”), which, inter alia, are useful in the treatment of cancer, e.g., cancer characterized by (e.g., driven by) mutant RAS (“mutant RAS cancer”). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions in the treatment of cancer, e.g., mutant RAS cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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