1- (5-tert-butyl-2-phenyl-2H-pyrazol-3-yl) -3- [2-fluoro-4- (1-methyl-2-oxo-2,3-dihydro-1H-imidazo [ 4,5-B] PYRIDIN-7-YLOXY) -PHENYL] -UREA AND ASSOCIATED COMPOUNDS AND THEIR USE IN THERAPY

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专利权人:

CANCER RESEARCH TECHNOLOGY LIMITED;THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL

发明人:

SPRINGER, CAROLINE,NICULESCU-DUVAZ, ION,MARAIS, RICHARD,NICULESCU-DUVAZ, DAN,ZAMBON, ALFONSO,MENARD, DELPHINE

申请号：

DK11701856

公开号：

DK2531502T3

申请日:

2011.01.27

申请国别(地区):

DK

年份:

2014

代理人:

摘要：

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain compounds of the following formula (I) (for convenience, collectively referred to herein as &ldquo；IP compounds&rdquo；), which, inter alia, are useful in the treatment of cancer, e.g., cancer characterized by (e.g., driven by) mutant RAS (&ldquo；mutant RAS cancer&rdquo；). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions in the treatment of cancer, e.g., mutant RAS cancer.

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