FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;ALBERT-LUDWIGS-UNIVERSITAT FREIBURG
发明人:
GRUNWALD, INGO,RICHTER, KATHARINA,MIERNIK, ARKADIUSZ,SCHOENTHALER, MARTIN
申请号：
CA2910164
公开号：
CA2910164A1
申请日:
2013.08.22
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Described is a kit for producing a crosslinked gel for surrounding urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, comprising a composition (A) comprising one or more cationically crosslinkable polymers, and a composition (B) comprising one or more crosslinking agents for crosslinking the cationically crosslinkable polymer(s). The compositions (A) and/or (B) further comprise magnetizable particles, or the kit further comprises a composition (C) that comprises magnetizable particles. On contact between compositions (A) and (B) in a region of the urinary tract, more particularly the kidney, that contains urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, a crosslinked gel is formed that partly or fully surrounds the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, and that comprises the magnetizable particles. The gel together with the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, can then be removed from the body by using magnetic interactions.
