Markus Kalkum,Karine Bagramyan,Diana Diaz-Arevalo,James I. Ito,Sanjeet Dadwal
申请号：
US15236988
公开号：
US10648982B2
申请日:
2016.08.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are methods for detecting an Aspergillus protease in a sample, diagnosing a subject with aspergillosis caused by an Aspergillus infection based on the presence of an Aspergillus protease in a sample, and methods of aspergillosis treatment that incorporate these diagnostic methods. In certain embodiments, the Aspergillus protease is Asp f2, and the Aspergillus infection is caused A. fumigatus, A. flavus, A. versicolor, A. niger, or A. terreus. Also provided herein are antibodies and kits for use in these methods, including novel antibodies specific for Asp f2.
