The Board of Regents of the University of Texas System;VANDERBILT UNIVERSITY
发明人:
James E. CROWE, Jr.,Andrew I. FLYAK,Alexander BUKREYEV,Philipp ILINYKH
申请号:
US16790658
公开号:
US20200200749A1
申请日:
2020.02.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the iminunodetection methods described above.