Oliver Petermann,Matthias Sprehe,Meinolf Brackhagen,Steven J. Guillaudeu
申请号:
US14421064
公开号:
US20150202301A1
申请日:
2013.08.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Esterified cellulose ethers which have i) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, ii) a weight average molecular weight Mw of from 80,000 Dalton to 350,000 Dalton, iii) a Polydispersity Mw/Mn of from 1.3 to 4.1, and iv) a viscosity of up to 4.0 mPa s, measured as a 2.0 wt % solution of the esterified cellulose ether in 0.43 wt % aqueous NaOH at 20° C., are useful as enteric polymers for pharmaceutical dosage forms.