METHODS FOR TRIGGERING DE NOVO FORMATION OF HETEROCHROMATIN AND OR EPIGENETIC SILENCING WITH SMALL RNAS

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专利权人:

发明人:

申请号：

EP15741336.0

公开号：

EP3157535A1

申请日:

2015.06.22

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present application relates to a method for the targeted formation of heterochromatin and/or induction of epigenetic gene silencing in a cell using a small RNA, said method comprising the step of inhibiting the Paf1 complex in said cell and the step of contacting said cell with a small RNA targeted to a region of the genome of the cell, said region being the region where heterochromatin formation and/or induction of epigenetic gene silencing should be induced.

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中国工程科技知识中心

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