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Prognostic for hematological malignancy
专利权人:
Veridex; LLC
发明人:
Raponi, Mitch
申请号:
AU2012202170
公开号:
AU2012202170A1
申请日:
2012.04.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012202170A120120503.pdf#####ABSTRACT Methods for treating cancer, and preferably hematological malignancy, patients include analyzing gene expression profiles and/or molecular markers of a patient to determine status and/or prognosis of the patient. The invention also provides methods of analyzing whether a non-relapsed or non-refractory patient is likely to respond to treatment with farnesyl transferase inhibitors (FTIs) and, optionally, other therapeutics. The methods are also useful for monitoring patient therapy and for selecting a course of therapy. Genes modulated in response to FTI treatment are provided and are used in formulating the profiles.Figure 1. H II i: IV v vi ~M Lnzr0 =n
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