The disclosed invention generally relates to pharmaceutical and nutraceutical compounds and methods for reducing neuropathic pain and depression caused by toxicity, metabolism abnormality, trauma, compression, autoimmune abnormality, congenital/hereditary abnormality, infection, abnormally activated neuronal circuits, emotional stress, chemical imbalance, mental health disorder, or other causes in subjects in need thereof. The disclosed invention further relates to naturally occurring, synthetic and semi-synthetic multifunctional compounds that exhibit antidepressant and analgesic activity where said compound contains a pharmacologically inactive substance.
