PROVIDED ARE ANTI-WRINKLE AGENTS HAVING A NOVEL SCAFFOLD THAT IS SUITABLE AS COMPONENTS FOR EXTERNAL SKIN PREPARATIONS SUCH AS COSMETICS. THE ANTI-WRINKLE AGENTS COMPRISE COMPOUNDS REPRESENTED BY GENERAL FORMULA (1) , STEREOISOMERS THEREOF, OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF. SAID ANTI-WRINKLE AGENTS HAVE EXCELLENT EFFICACY IN IMPROVING WRINKLES AND SAGGING THAT ARE CAUSED BY SKIN AGING WITH INCREASED AGE OR OCCUR AS A RESULT OF PHOTOAGING DUE TO ULTRAVIOLET RAYS EXPOSURE. [IN THE FORMULA, R1 REPRESENTS A HYDROGEN ATOM OR A 1 TO 8 CARBON STRAIGHT OR BRANCHED ALKYL GROUP. R2 REPRESENTS – SH, -SO3H, -S-S-X1, -S-X2, -SO-X3, -SO2-X4, -SO2-NY1-X5 OR –SO2-NY2-Y3. X1-X5 INDEPENDENTLY ARE HYDROGEN ATOMS OR 1 TO 8 CARBON ALIPHATIC HYDROCARBON GROUPS OR 5 TO 12 CARBON AROMATIC MOIETY WHEREIN CARBON ATOMS MAY BE SUBSTITUTED WITH HETEROATOMS. Y1 TO Y3 INDEPENDENTLY REPRESENT HYDROGEN ATOMS OR 1 TO 8 CARBON LINEAR OR BRANCHED ALKYL GROUPS. R3 REPRESENTS A HYDROGEN ATOM OR ACYL GROUP HAVING A 1 TO 8 CARBON STRAIGHT OR BRANCHED ALKYL CHAIN. R4 REPRESENTS A 5 TO 12 CARBON AROMATIC GROUP OR POLYCYCLIC CONDENSED AROMATIC GROUP THAT MAY HAVE UNSUBSTITUTED OR SUBSTITUTED GROUPS. M REPRESENTS AN INTEGER 0-3 AND N REPRESENTS AN INTEGER 1 TO OR 2].
