A composition for alleviating hangover symptoms in a subject in need thereof. The composition comprises dihydromyricetin, N-Acetyl Cysteine, taurine, salicin, niacin, vitamin B6, selenium, manganese and prickly pear powder. The composition can be formulated as pills or capsules. The dihydromyricetin component may be coated with soy lecithin to maximize absorption. The composition includes a first composition and a separate second composition. The composition is administered as a first pill or capsule comprising the first composition prior to alcohol consumption and a second pill comprising the first composition taken after alcohol consumption.
