Mellon, Christophe,Isabel, Elise,Beaulieu, Christian
申请号:
AU2008329515
公开号:
AU2008329515B2
申请日:
2008.11.26
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Several parasites responsible for mammalian diseases are dependent on cysteineprotease for various life-cycle functions. Inhibition or decreasing functionof these proteases can be useful in the treatment and/or prevention of these parasiticdiseases including; toxoplasmosis, malaria, African trypanosomiasis, Chagasdisease, leishmaniasis, schistosomiasis, amebiasis, giardiasis, clonorchiasis,opisthorchiasis, paragonimiasis, fasciolopsiasis, lymphatic filariasis,onchocerciasis, dracunculiasis, ascariasis, trichuriasis, strongyloidiasis,trichostrongyliasis, trichomoniasis or cestodiasis. Compounds of formulaI of the invention are capable of treating and/or preventing the above-identifieddiseases: