The invention relates to new pyridopyrazine and naphthyridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.本發明係有關於一種新穎的吡啶吡嗪和二氮雜萘衍生化合物、包含所述化合物之醫藥組成物、用於製備所述化合物之製程以及所述化合物於如癌症之疾病之治療用途。