A drive arrangement for a harvesting header of a harvesting machine is provided. The harvesting machine has a running gear on which a feeder housing is fastened. On the front side of the feeder housing a fastening device that can move relative to the feeder housing is attached. On the fastening device, a harvesting header can be attached. The drive arrangement comprises a harvesting header-driven shaft that can be set in rotation by the harvesting machine and is coupled with the fastening device and can move with the fastening device relative to the feeder housing. A harvesting header drive shaft of the harvesting header can be connected to the harvesting header-driven shaft. It is further provided that a coupling with two coupling halves is attached between the harvesting header-driven shaft and the harvesting header drive shaft, with these coupling halves separating automatically when the harvesting header is disassembled from the feeder housing and connecting automatically when the harvesting header, is attached on the feeder housing.