Provided is an apparatus, a system and method for use in image guided medical instrument manipulation. Embodiments describe various apparatuses having a mount operable to receive an imaging probe, a body guide and a medical instrument guide. There are also described methods and a systems for using the various apparatuses to position the apparatus and collect data relating to the position of the medical instrument relative to a target within a patient's body. Further methods include using the apparatus and system in epidural anaesthetic procedure or lumbar puncture. The apparatus may include a hand-held ultrasound probe, configured to acquire a volumetric dataset representing a 3-D depiction of a volume, which may include information about a medical instrument's position relative to the target in three dimensions.