CHENG HENGMIAO,KATH JOHN CHARLES,NAGATA ASAKO,JOHNSON JR. THEODORE OTTO,LIU KEVIN KUN-CHIN,LUNNEY ELIZABETH ANN,NAIR SAJIV KRISHNAN,PLANKEN SIMON PAUL,SUTTON SCOTT CHANNING
申请号：
CL2014002726
公开号：
CL2014002726A1
申请日:
2014.10.09
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and m are defined herein. There novel pyrrolopyrimidine and purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.Compuestos derivados de 7H-pirrolo[2,3-d]pirimidina y 9H-purina； composición farmacéuticas que los comprende； y su uso en el tratamiento del crecimiento celular anormal en un mamífero” (divisional de la solicitud CL 566-14)
