Pirrolopirimidina and purine derived compounds and their pharmaceutically acceptable salts, Pharmaceutical composition that is useful for the treatment of abnormal cell growth, such as cancer.
CHENG HENGMIAO,JOHNSON JR THEODORE OTTO,KATH JOHN CHARLES,LIU KEVIN KUN-CHIN,LUNNEY ELIZABETH ANN,NAGATA ASAKO,NAIR SAJIV KRISHNAN,PLANKEN SIMON PAUL,SUTTON SCOTT CHANNING
申请号：
CL2014000566
公开号：
CL2014000566A1
申请日:
2014.10.09
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and m are defined herein. There novel pyrrolopyrimidine and purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.COMPUESTOS HETEROCICLICOS DERIVADOS DE 7H-PIRROLO-[2,3-D]-PIRIMIDINA Y 9H-PURINA； SUS COMPOSICIONES FARMACOLOGICAS； UTILES PARA EL TRATAMIENTO DEL CRECIMIENTO CELULAR ANORMAL, TAL COMO CANCER.
