A method of monitoring medication regimen complemented with portable apparatus is disclosed and including following steps: a patient logins the portable apparatus through personal features; capturing an image of a blister package through the portable apparatus; recognizing the image for obtaining an identification tag of the blister package’s exterior appearance; comparing the patient’s identity with the identification label; displaying a warning on the portable apparatus when the patient’s identity doesn’t match with the identification tag; and, automatically recording the patient’s medication intake time and remaining medication count of the blister package when the patient’s identity matches with the identification tag. The method may avoid false medication intake and help the pharmacists and nurses to track the patient’s medication intake time and the remaining medication count in real-time, which would also improve patient’s medication compliance.一種藉由行動裝置實現的藥片服用輔助方法,包括下列步驟:病患使用個人特徵登入行動裝置;通過行動裝置拍攝藥包影像;分析藥包影像以取得藥包上的獨特標籤;比對病患身份與獨特標籤;於病患身份與獨特標籤比對不符時於行動裝置上顯示警示訊息;及,於病患身份與獨特標籤比對相符時,自動記錄病患的服藥時間以及藥包中的藥片的剩餘數量。本發明藉由比對病患身份與藥包的獨特標籤可避免病患服錯藥,並且藉由自動記錄服藥時間及藥片的剩餘數量可供藥劑師或護士進行追蹤,以提升病患的服藥遵循率。