The present invention relates to the pharmaceutically acceptable salts of (R)-7-[3-amino-4-(2,4,5-trifluo-phenyl)-butyryl]-3-trifluomethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid methyl ester, preparation method thereof and the use of said salts in the preparation of an antidiabetic medicament.本發明公開了(R)-7-[3-胺基-4-(2,4,5-三氟-苯基)-丁醯]-3-三氟甲基-5,6,7,8-四氫-咪唑並[1,5-a]吡嗪-1-羧酸甲酯的藥學上可接受的鹽,其製備方法以及在製備抗糖尿病藥物中的用途。