TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES SALTS, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF

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专利权人:

JIANGSU HENGRUI MEDICINE CO.; LTD.

发明人:

TANG, PENG CHO,邓炳初,鄧炳初,SUN, PIAOYANG,孙飘扬,孫飄揚,YANG, FANGLONG,杨方龙,楊方龍,LIANG, JINDONG,梁金栋,梁金棟,SHEN, GUANGYUAN,沈光远,沈光遠,WANG, YANG,王阳,王陽,FAN, JIANG,范江,範江

申请号：

TW099129616

公开号：

TWI522358B

申请日:

2010.09.02

申请国别(地区):

TW

年份:

2016

代理人:

摘要：

The present invention relates to (R)-7-[3-Amino-4-(2,4,5-trifluoro-phenyl)-butyryl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid pharmaceutical salts, methods for their preparation, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as a dipeptidyl peptidase IV inhibitor.本發明涉及(R)-7-[3-胺基-4-(2,4,5-三氟苯基)-丁醯基]-3-三氟甲基-5,6,7,8-四氫咪唑并[1,5-a]吡-1-甲酸可藥用的鹽、其製備方法以及含有該可藥用鹽的醫藥組成物、以及其作為治療劑特別是作為二肽基肽酶IV(DPPIV)抑制劑的用途。

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/