PROTÉINES DE FUSION ASSOCIÉES À LA FOLLISTATINE ET LEURS UTILISATIONS

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专利权人:

Acceleron Pharma Inc.

发明人:

KUMAR, Ravindra,GRINBERG, Asya,SAKO, Dianne S.

申请号：

EP16769819

公开号：

EP3274457A4

申请日:

2016.03.25

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

In certain aspects, the present disclosure provides compositions and methods for inhibiting activity of TGFβ superfamily ligands, particularly ligands such as GDF8, GDF11, activin A, activin B, activin C and activin E, in vertebrates, including rodents and primates, and particularly in humans. In some embodiments, the compositions of the disclosure may be used to treat or prevent diseases or disorders that are associated with abnormal activity of a follistatin-related polypeptide and/or a follistatin ligand.

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