Jiawang LIU,Nanmeng SONG,Dongge YANG,Yaping YANG,Maengsup KIM
申请号：
US16337854
公开号：
US20190284299A1
申请日:
2017.09.28
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides a method for production of stable and highly specific heterodimeric immunoglobulin constructs, e.g., bispecific antibodies, retaining desirable properties of native IgG and lacking undesirable heavy chain-light chain mispairing, that can simultaneously bind two target molecules and are more potent in the treatment of complex diseases.
