KIM, Maengsup,LIU, Jiawang,SONG, Nanmeng,YANG, Dongge,YANG, Yaping
申请号:
TN2019000055
公开号:
TN2019000055A1
申请日:
2017.09.28
申请国别(地区):
TN
年份:
2020
代理人:
摘要:
Provided is a method for production of stable and highly specific heterodimeric immunoglobulin constructs, e.g., bispecific antibodies, retaining desirable properties of native IgG and lacking undesirable heavy chain-light chain mispairing, that can simultaneously bind two target molecules and are more potent in the treatment of complex diseases.