HAAS, HEINRICH,HORNER, SEBASTIAN,ESPARZA BORQUEZ, ISAAC HERNAN,HILLER, THOMAS MICHAEL,BATES, FERDIA
申请号：
CA3078292
公开号：
CA3078292A1
申请日:
2018.10.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to methods for preparing RNA lipoplex particles for delivery of RNA to target tissues after parenteral administration, in particular after intravenous administration, and compositions comprising such RNA lipoplex particles. The present disclosure also relates to methods which allow preparing RNA lipoplex particles in an industrial GMP-compliant manner. Furthermore, the present disclosure relates to methods and compositions for storing RNA lipoplex particles without substantial loss of the product quality and, in particular, without substantial loss of RNA activity.
