Bret M. Berry;Mahendra S. Rao;Darrel S. Brodke;Ramaswamy Lakshminarayanan;Ashok C. Khandkar
发明人:
Darrel S. Brodke,Bret M. Berry,Ashok C. Khandkar,Ramaswamy Lakshminarayanan,Mahendra S. Rao
申请号：
US13538559
公开号：
US20130030531A1
申请日:
2012.06.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
An improved bone graft is provided for human implantation, particularly such as a spinal fusion cage for implantation into the inter-vertebral space between two adjacent vertebrae. The improved spinal fusion cage includes a substrate block of high strength biocompatible material having a selected size and shape to fit the anatomical space, and a controlled porosity analogous to natural bone. The substrate block may be coated with a bio-active surface coating material such as hydroxyapatite or a calcium phosphate to promote bone ingrowth and enhanced bone fusion. Upon implantation, the fusion cage provides a spacer element having a desired combination of mechanical strength together with osteoconductivity and osteoinductivity to promote bone ingrowth and fusion, as well as radiolucency for facilitated post-operative monitoring. The fusion cage may additionally carry one or more natural or synthetic therapeutic agents for further promoting bone ingrowth and fusion.
