Chapman, Robert,Rider, Lonn S.,Hong, Qi,Kyle, Donald,Kupper, Robert
申请号:
AU2013202453
公开号:
AU2013202453A1
申请日:
2013.04.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013202453A120130502.pdf#####PROCESS FOR PREPARING OXYCODONE HYDROCHLORIDE HAVING LESS THAN 25 PPM 14-HYDROXYCODEINONE Abstract Oxycodone is a semi-synthetic opioid analgesic that exerts an agonist effect at specific, saturatable opioid receptors in the CNS and other tissues. 14-hydroxycodeinone is an impurity formed in the production of oxycodone from thebaine. The invention provides a purified oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and processes for its production.