Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone

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专利权人:

Purdue Pharma L.P.

发明人:

Chapman, Robert,Rider, Lonn S.,Hong, Qi,Kyle, Donald,Kupper, Robert

申请号：

AU2015261590

公开号：

AU2015261590B2

申请日:

2015.11.25

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2015261590B220170420.pdf#####PROCESS FOR PREPARING OXYCODONE HYDROCHLORIDE HAVING LESS THAN 25 PPM 14-HYDROXYCODEINONE Abstract Oxycodone is a semi-synthetic opioid analgesic that exerts an agonist effect at specific, saturatable opioid receptors in the CNS and other tissues. 14-hydroxycodeinone is an impurity formed in the production of oxycodone from thebaine. The invention provides a purified oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and processes for its production.

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