DRUGS OF CYTOTOXIC MEDICINES CONTAINING ENZYMATLY DIVISIBLE GROUPS

• 收藏
• 分享

专利权人:

БАЙЕР ФАРМА АКЦИЕНГЕЗЕЛЬШАФТ (DE)

发明人:

ЛЕРХЕН Ханс-Георг (DE),РЕБШТОК Анне-Софи (FR),МАРКС Лео (CH),ЙОХАННЕС Сара Анна Лиза (DE),ШТЕЛЬТЕ-ЛЮДВИГ Беатрикс (DE),ДИТЦ Лиза (DE),ТЕРЬЮНГ Карстен (DE),МАЛЕРТ Кристоф (DE),ГРЕФЕН Зимоне (DE),ЗОММЕР

申请号：

RU2018136778

公开号：

RU2018136778A

申请日:

2017.03.21

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

in which cytotoxic drugs, for example kinesin spindle protein inhibitors, are masked with legumain-cleavable groups and hence release the drug, and to the use of these prodrugs or conjugates for treatment and/or prevention of diseases, and to the use of these prodrugs or conjugates for production of medicaments for treatment and/or prevention of diseases, especially of hyperproliferative and/or angiogenic disorders, for example cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/