DENG, SHIXIAN;PURGATORIO, ROSA;FIORITO, JOLE;ARANCIO, OTTAVIO;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;LANDRY, DONALD W.
发明人:
ARANCIO, OTTAVIO,DENG, SHIXIAN,LANDRY, DONALD W.,FIORITO, JOLE,PURGATORIO, ROSA,O'CONNOR, OWEN ANTHONY,AMENGUAL, JENNIFER EFFIE,OCONNOR, OWEN ANTHONY
申请号:
CA2944613
公开号:
CA2944613A1
申请日:
2015.03.30
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.