Eugene T. Michal,Daniel J. Lerner,Matthew J. Pollman
申请号：
US12558420
公开号：
US09198968B2
申请日:
2009.09.11
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.
