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Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
专利权人:
Covidien LP
发明人:
Michal, Eugene T.,Lerner, Daniel J.,Pollman, Matthew J.
申请号:
AU2009291552
公开号:
AU2009291552B2
申请日:
2009.09.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.
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