A clam shell shaped adapter for connecting a fluid output device and a fluid input device to establish a fluid path between the fluid output and input devices has first and second shells integrally connected by a living hinge. The first shell has a connector fitting end and a catheter end connected by a tubing. The fluid output device may be a catheter that is matable to the catheter end. A retainer structure in the adapter fixedly retains the catheter when the first and second shells close upon each other. Respective latch mechanisms provided at the first and second shells lockingly couple the first and second shells to each other. The fitting end has a given configuration that prevents the fitting end from mating with a counterpart conventional luer fitting but enables the fitting end to mate with a counterpart connector fitting that has a special configuration that mirrors the given configuration.