Manufacture of 2-(5-bromo-4(-cyclopropylnaphthalen-1-yl)-4h-1,2,4-triazol-3-ylthio)acetic acid

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专利权人:

ARDEA BIOSCIENCES INC.

发明人:

GUNIC ESMIR,GALVIN GABRIEL

申请号：

NZ63104413

公开号：

NZ631044A

申请日:

2013.07.02

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Disclosed is processes for the synthesis of 2-(S-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl-thio)acetic acid (compound of formula III) comprising brominating a precursor compound with N-bromosuccinimide (NBS) and a solvent.

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