Anthony O. CAGGIANO,Andrea VECCHIONE,Jennifer IACI
申请号:
US15230040
公开号:
US20170028038A1
申请日:
2016.08.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure relates to protein and nucleic acid mutants of chondroitinase ABCI. Such nucleic acid mutants encode for chondroitinase ABCI mutant enzymes exhibiting altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using such nucleic acid mutants encoding chondroitinase ABCI mutant enzymes is also provided.