Anthony O. Caggiano,Andrea Vecchione,Jennifer Iaci
申请号:
US13849420
公开号:
US09102930B2
申请日:
2013.03.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure relates to protein and nucleic acid mutants of chondroitinase ABCI. Such nucleic acid mutants encode for chondroitinase ABCI mutant enzymes exhibiting altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using such nucleic acid mutants encoding chondroitinase ABCI mutant enzymes is also provided.